Stressed rats keep returning to cannabis and scientists know why

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Rats with naturally high stress levels were far more likely to self-administer cannabis when given access. Behavioral testing showed that baseline stress hormones were the strongest predictor of cannabis-seeking behavior. Lower cognitive flexibility and low endocannabinoid levels also contributed to increased use. The results hint at possible early indicators of vulnerability to drug misuse.

Source: https://www.sciencedaily.com/releases/2 ... 100615.htm